PPP1R1A antibody

Catalog No. ABIN6264384

Product Details anti-PPP1R1A Antibody

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: PPP1R1A Antibody detects endogenous levels of total PPP1R1A

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PPP1R1A

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for PPP1R1A

Target: PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))

Alternative Name: PPP1R1A (PPP1R1A Products)

Synonyms: I1 antibody, IPP1 antibody, 0610038N18Rik antibody, I-1 antibody, pil antibody, IPP-1 antibody, protein phosphatase 1 regulatory inhibitor subunit 1A antibody, protein phosphatase 1, regulatory (inhibitor) subunit 1A antibody, protein phosphatase 1 regulatory inhibitor subunit 1A L homeolog antibody, PPP1R1A antibody, Ppp1r1a antibody, ppp1r1a.L antibody

Background:

Description: Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Gene: PPP1R1A

Molecular Weight: 27 kDa

Gene ID: 5502

UniProt: Q13522

Pathways: Cellular Glucan Metabolic Process