PLTP antibody (Internal Region)

Catalog No. ABIN6264310

Product Details anti-PLTP Antibody

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLTP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: PLTP Antibody detects endogenous levels of total PLTP.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PLTP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PLTP

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Alternative Name: PLTP (PLTP Products)

Synonyms: zgc:100903 antibody, MGC84445 antibody, PLTP antibody, hdlcq9 antibody, DKFZp469A1437 antibody, BPIFE antibody, HDLCQ9 antibody, Bpife antibody, OD107 antibody, phospholipid transfer protein antibody, phospholipid transfer protein S homeolog antibody, PLTP antibody, pltp antibody, pltp.S antibody, LOC542343 antibody, Pltp antibody

Background:

Description: Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.

Gene: PLTP

Molecular Weight: 54kDa

Gene ID: 5360

UniProt: P55058

Pathways: Lipid Metabolism