PLEC antibody (N-Term)

Catalog No. ABIN6264300

Product Details anti-PLEC Antibody

Target: PLEC (Plectin (PLEC))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEC antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: PLEC Antibody detects endogenous levels of total PLEC.

Predicted Reactivity: Bovine,Horse

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PLEC, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PLEC

Target: PLEC (Plectin (PLEC))

Alternative Name: PLEC (PLEC Products)

Synonyms: EBS1 antibody, EBSO antibody, HD1 antibody, LGMD2Q antibody, PCN antibody, PLEC1 antibody, PLEC1b antibody, PLTN antibody, AA591047 antibody, AU042537 antibody, Plec1 antibody, Pcn antibody, Pltn antibody, IFAP300 antibody, Plectin-1 antibody, plectin antibody, plectin L homeolog antibody, LOC100481602 antibody, plec.L antibody, PLEC antibody, Plec antibody, LOC786966 antibody

Background:

Description: Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.

Gene: PLEC

Molecular Weight: 531 kDa

Gene ID: 5339

UniProt: Q15149