Pallidin antibody (C-Term)

Catalog No. ABIN6264299

Product Details anti-Pallidin Antibody

Target: Pallidin (PLDN) (Pallidin Homolog (PLDN))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pallidin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: PLDN Antibody detects endogenous levels of total PLDN.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PLDN, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Pallidin

Target: Pallidin (PLDN) (Pallidin Homolog (PLDN))

Alternative Name: BLOC1S6 (PLDN Products)

Synonyms: CG14133 antibody, Dmel\\CG14133 antibody, LOC100226487 antibody, pldn antibody, BLOS6 antibody, HPS9 antibody, PA antibody, PALLID antibody, PLDN antibody, Pldn antibody, BLOC-1 antibody, Stx13bp1 antibody, pa antibody, pallidin antibody, CG14133 gene product from transcript CG14133-RB antibody, biogenesis of lysosomal organelles complex 1 subunit 6 antibody, pallidin homolog (mouse) antibody, biogenesis of lysosomal organelles complex-1, subunit 6, pallidin antibody, Pallidin antibody, BLOC1S6 antibody, pldn antibody, Bloc1s6 antibody

Background:

Description: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

Gene: BLOC1S6

Molecular Weight: 25 kDa

Gene ID: 26258

UniProt: Q9UL45

Pathways: Synaptic Vesicle Exocytosis