PDE4B/C/D antibody

Catalog No. ABIN6264092

Product Details anti-PDE4B/C/D Antibody

Target: PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4B/C/D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: PDE4B/C/D Antibody detects endogenous levels of total PDE4B/C/D

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PDE4B/C/D

Isotype: IgG

Application Details

Application Notes: WB 1:1000 IHC 1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for PDE4B/C/D

Target: PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))

Alternative Name: PDE4B/C/D (PDE4B/C/D Products)

Background:

Description: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.

Gene: PDE4B

Molecular Weight: 76kDa

Gene ID: 5142

UniProt: Q07343, Q08493, Q08499