PCMT1 antibody (Internal Region)

Catalog No. ABIN6264069

Product Details anti-PCMT1 Antibody

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PCMT1 Antibody detects endogenous levels of total PCMT1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PCMT1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PCMT1

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Alternative Name: PCMT1 (PCMT1 Products)

Synonyms: PIMT antibody, C79501 antibody, PCM antibody, PCMT antibody, etID309741.20 antibody, fj13d06 antibody, pimt antibody, wu:fj13d06 antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 antibody, protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog antibody, protein-L-isoaspartate(D-aspartate)O-methyltransferase antibody, PCMT1 antibody, Pcmt1 antibody, pcmt1.L antibody, pcmt1 antibody, pcmt antibody

Background:

Description: Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.

Gene: PCMT1

Molecular Weight: 25 kDa

Gene ID: 5110

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization