Parvin, beta antibody (C-Term)

Catalog No. ABIN6264044

Product Details anti-Parvin, beta Antibody

Target: Parvin, beta (PARVB)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Parvin, beta antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PARVB Antibody detects endogenous levels of total PARVB.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PARVB, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Parvin, beta

Target: Parvin, beta (PARVB)

Alternative Name: PARVB (PARVB Products)

Synonyms: affixin antibody, beta-parvin antibody, fd02e01 antibody, wu:fd02e01 antibody, zgc:73117 antibody, CGI-56 antibody, AI595373 antibody, AW742462 antibody, D15Gsk1 antibody, parvin beta antibody, parvin, beta antibody, parvin beta S homeolog antibody, parvb antibody, PARVB antibody, parvb.S antibody, Parvb antibody

Background:

Description: Adapter protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Is involved in the reorganization of the actin cytoskeleton and formation of lamellipodia. Plays a role in cell adhesion, cell spreading, establishment or maintenance of cell polarity, and cell migration.

Gene: PARVB

Molecular Weight: 42 kDa and 45 kDa

Gene ID: 29780

UniProt: Q9HBI1