PA2G4 antibody (C-Term)

Catalog No. ABIN6264002

Product Details anti-PA2G4 Antibody

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PA2G4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: PA2G4 Antibody detects endogenous levels of total PA2G4.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PA2G4, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Alternative Name: PA2G4 (PA2G4 Products)

Synonyms: EBP1 antibody, HG4-1 antibody, p38-2G4 antibody, Ebp1 antibody, pa2g4 antibody, si:dz150i12.2 antibody, wu:fb19b11 antibody, wu:ft56d05 antibody, zgc:86732 antibody, ebp1 antibody, hg4-1 antibody, p38-2g4 antibody, pa2g4-a antibody, PA2G4 antibody, DKFZp469G2132 antibody, Pa2g4 antibody, MGC81621 antibody, 38kDa antibody, AA672939 antibody, Plfap antibody, proliferation-associated 2G4 antibody, proliferation-associated 2G4, a antibody, proliferation-associated 2G4, 38kDa antibody, proliferation-associated 2G4 L homeolog antibody, proliferation-associated protein 2G4 antibody, proliferation-associated 2G4 S homeolog antibody, proliferation-associated protein 2G4 pseudogene antibody, PA2G4 antibody, Pa2g4 antibody, pa2g4a antibody, pa2g4.L antibody, pa2g4 antibody, LOC100519773 antibody, pa2g4.S antibody, LOC693641 antibody

Background:

Description: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).

Gene: PA2G4

Molecular Weight: 43kDa

Gene ID: 5036

UniProt: Q9UQ80

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades