OAZ2 antibody (Internal Region)

Catalog No. ABIN6263788

Product Details anti-OAZ2 Antibody

Target: OAZ2 (Ornithine Decarboxylase Antizyme 2 (OAZ2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAZ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: OAZ2 Antibody detects endogenous levels of total OAZ2.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human OAZ2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for OAZ2

Target: OAZ2 (Ornithine Decarboxylase Antizyme 2 (OAZ2))

Alternative Name: OAZ2 (OAZ2 Products)

Synonyms: AZ2 antibody, AZ-2 antibody, Oaz2-ps antibody, Sez15 antibody, AZL antibody, oaz2 antibody, wu:fa14f04 antibody, zgc:63816 antibody, RGD1562933 antibody, si:dkey-275p19.6 antibody, ornithine decarboxylase antizyme 2 antibody, ornithine decarboxylase antizyme 1b antibody, ornithine decarboxylase antizyme 2 S homeolog antibody, ornithine decarboxylase antizyme 2a antibody, OAZ2 antibody, Oaz2 antibody, oaz1b antibody, oaz2.S antibody, Tsp_12111 antibody, oaz2 antibody, oaz2a antibody

Background:

Description: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity (PubMed:17900240). Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol (By similarity).

Gene: OAZ2

Molecular Weight: 21 kDa

Gene ID: 4947

UniProt: O95190