SLC22A6 antibody (Internal Region)

Catalog No. ABIN6263787

Product Details anti-SLC22A6 Antibody

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC22A6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: SLC22A6 Antibody detects endogenous levels of total SLC22A6.

Predicted Reactivity: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SLC22A6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for SLC22A6

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Alternative Name: SLC22A6 (SLC22A6 Products)

Synonyms: HOAT1 antibody, OAT1 antibody, PAHT antibody, ROAT1 antibody, NKT antibody, Oat1 antibody, Orctl1 antibody, mOat1 antibody, slc22a6 antibody, zgc:77073 antibody, SLC22A6 antibody, Paht antibody, Roat1 antibody, nkt antibody, oat1 antibody, oat1-B antibody, paht antibody, roat1 antibody, slc22a6-B antibody, Slc22a6 antibody, solute carrier family 22 member 6 antibody, solute carrier family 22 (organic anion transporter), member 6 antibody, solute carrier family 22 (organic anion transporter), member 6, like antibody, Solute carrier family 22 member 6 antibody, solute carrier family 22 (organic anion transporter), member 6 S homeolog antibody, SLC22A6 antibody, Slc22a6 antibody, slc22a6l antibody, s22a6 antibody, slc22a6.S antibody

Background:

Description: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP) and edaravone sulfate. PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), sulindac, diclofenac, carprofen, glutarate and okadaic acid (By similarity). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, furosemide, indomethacin, bumetamide, losartan, probenecid, phenol red, urate, and alpha-ketoglutarate.

Gene: SLC22A6

Molecular Weight: 61 kDa

Gene ID: 9356

UniProt: Q4U2R8

Pathways: Dicarboxylic Acid Transport