NUP153 antibody (C-Term)

Catalog No. ABIN6263773

Product Details anti-NUP153 Antibody

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP153 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Nup153 Antibody detects endogenous levels of total Nup153.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Nup153, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Alternative Name: NUP153 (NUP153 Products)

Synonyms: CG4453 antibody, Dmel\\CG4453 antibody, NUP153 antibody, Nup 153 antibody, dNup153 antibody, dmNup153 antibody, nup153 antibody, NUCZINK antibody, B130015D15Rik antibody, C88147 antibody, HNUP153 antibody, N153 antibody, Nucleoporin 153kD antibody, nucleoporin 153 antibody, nucleoporin 153kDa L homeolog antibody, Nup153 antibody, NUP153 antibody, nup153.L antibody

Background:

Description: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).

Gene: NUP153

Molecular Weight: 154kDa

Gene ID: 9972

UniProt: P49790

Pathways: Protein targeting to Nucleus