GAR1 antibody (Internal Region)

Catalog No. ABIN6263690

Product Details anti-GAR1 Antibody

Target: GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NOLA1 Antibody detects endogenous levels of total NOLA1.

Predicted Reactivity: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NOLA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for GAR1

Target: GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))

Alternative Name: GAR1 (GAR1 Products)

Synonyms: 46.t00052 antibody, Tb04.5D20.620 antibody, NOLA1 antibody, Nola1 antibody, AA409823 antibody, AI326794 antibody, C430047J18Rik antibody, nola1 antibody, zgc:56086 antibody, GAR1 homolog, ribonucleoprotein antibody, snoRNP protein gar1 antibody, snoRNP protein GAR1 antibody, GAR1 ribonucleoprotein antibody, gar1 antibody, EHI_194040 antibody, Tc00.1047053510687.120 antibody, Tb927.4.470 antibody, PVX_122305 antibody, Bm1_39105 antibody, CMU_040070 antibody, LOAG_03932 antibody, GAR1 antibody, Gar1 antibody

Background:

Description: Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Gene: GAR1

Molecular Weight: 22 kDa

Gene ID: 54433

UniProt: Q9NY12