NDRG1 antibody (C-Term)

Catalog No. ABIN6263554

Product Details anti-NDRG1 Antibody

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NDRG1 Antibody detects endogenous levels of total NDRG1.

Predicted Reactivity: Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NDRG1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1 (NDRG1 Products)

Synonyms: CAP43 antibody, CMT4D antibody, DRG-1 antibody, DRG1 antibody, GC4 antibody, HMSNL antibody, NDR1 antibody, NMSL antibody, PROXY1 antibody, RIT42 antibody, RTP antibody, TARG1 antibody, TDD5 antibody, Ndr1 antibody, Ndrl antibody, cap43 antibody, cmt4d antibody, drg1 antibody, gc4 antibody, hmsnl antibody, ndr1 antibody, ndrg1 antibody, nmsl antibody, proxy1 antibody, rit42 antibody, rtp antibody, targ1 antibody, tdd5 antibody, xndrg1 antibody, ndrg4 antibody, cb775 antibody, wu:fb60h02 antibody, zgc:63944 antibody, NDRG1 antibody, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN antibody, non race-specific disease resistance 1 antibody, ndrg1-a antibody, ndrg1-b antibody, xNDRG1-A antibody, ndrg1l antibody, zgc:73047 antibody, N-myc downstream regulated 1 antibody, N-myc downstream regulated gene 1 antibody, N-myc downstream regulated 1 S homeolog antibody, N-myc downstream regulated 1a antibody, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family antibody, N-myc downstream regulated 1 L homeolog antibody, N-myc downstream regulated 1b antibody, NDRG1 antibody, Ndrg1 antibody, ndrg1.S antibody, ndrg1 antibody, ndrg1a antibody, NDR1 antibody, ndrg1.L antibody, ndrg1b antibody

Background:

Description: Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy.

Gene: NDRG1

Molecular Weight: 43kDa

Gene ID: 10397

UniProt: Q92597