NASP antibody (C-Term)

Catalog No. ABIN6263518

Product Details anti-NASP Antibody

Target: NASP (Nuclear Autoantigenic Sperm Protein (Histone-Binding) (NASP))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NASP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: NASP Antibody detects endogenous levels of total NASP.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NASP, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NASP

Target: NASP (Nuclear Autoantigenic Sperm Protein (Histone-Binding) (NASP))

Alternative Name: NASP (NASP Products)

Synonyms: FLB7527 antibody, PRO1999 antibody, 5033430J04Rik antibody, AI131596 antibody, AI317140 antibody, D4Ertd767e antibody, Epcs32 antibody, Nasp-T antibody, wu:fd20g12 antibody, zgc:56007 antibody, zgc:85651 antibody, nuclear autoantigenic sperm protein antibody, nuclear autoantigenic sperm protein (histone-binding) antibody, NASP antibody, Nasp antibody, nasp antibody

Background:

Description: Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.

Gene: NASP

Molecular Weight: 138kDa

Gene ID: 4678

UniProt: P49321