Myosin XVIIIA antibody (Internal Region)
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- Target See all Myosin XVIIIA (MYO18A) Antibodies
- Myosin XVIIIA (MYO18A)
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Binding Specificity
- Internal Region
- Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Myosin XVIIIA antibody is un-conjugated
- Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MYO18A Antibody detects endogenous levels of total MYO18A.
- Predicted Reactivity
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MYO18A, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Myosin XVIIIA (MYO18A)
- Alternative Name
- MYO18A (MYO18A Products)
- Synonyms
- myosin-18 antibody, MYSPDZ antibody, SPR210 antibody, MyoPDZ antibody, MysPDZ antibody, myosin XVIIIa antibody, myosin XVIIIA antibody, unconventional myosin-XVIIIa antibody, myosin XVIIIA L homeolog antibody, Myosin XVIIIA antibody, myosin xviiia antibody, Myo18a antibody, MYO18A antibody, myo18a antibody, LOC100183025 antibody, myo18a.L antibody, LOC100640961 antibody, Bm1_54460 antibody, LOAG_04825 antibody
- Background
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Description: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).
Gene: MYO18A
- Molecular Weight
- 230 kDa,190 kDa
- Gene ID
- 399687
- UniProt
- Q92614
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