MX1 antibody (C-Term)

Catalog No. ABIN6263446

Product Details anti-MX1 Antibody

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: MX1 Antibody detects endogenous levels of total MX1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MX1, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1 (MX1 Products)

Synonyms: IFI78 antibody, AI893580 antibody, Mx antibody, Mx-1 antibody, IFI-78K antibody, MX antibody, MxA antibody, Mx1-b antibody, Mx1B antibody, OGTPBP antibody, ONBP antibody, myxovirus (influenza virus) resistance 1 antibody, MX dynamin-like GTPase 1 antibody, MX dynamin like GTPase 1 antibody, Mx1 antibody, MX1 antibody

Background:

Description: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Gene: MX1

Molecular Weight: 76kDa

Gene ID: 4599

UniProt: P20591