MTAP antibody (Internal Region)

Catalog No. ABIN6263418

Product Details anti-MTAP Antibody

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTAP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MTAP Antibody detects endogenous levels of total MTAP.

Predicted Reactivity: Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MTAP, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MTAP

Target: MTAP (Methylthioadenosine phosphorylase (MTAP))

Alternative Name: MTAP (MTAP Products)

Synonyms: BDMF antibody, DMSFH antibody, DMSMFH antibody, LGMBF antibody, MSAP antibody, c86fus antibody, Cc1-6 antibody, 1300019I21Rik antibody, MTAPase antibody, zgc:66012 antibody, mtap antibody, methylthioadenosine phosphorylase antibody, 5'-methylthioadenosine phosphorylase antibody, 6-oxopurine nucleoside phosphorylase antibody, methylthioadenosine phosphorylase L homeolog antibody, MTAP antibody, Mtap antibody, mtaP antibody, MMAH_RS04260 antibody, TAGG_RS05050 antibody, Toce_0364 antibody, VDIS_RS03165 antibody, MFER_RS02485 antibody, Intca_0886 antibody, DESMU_RS05370 antibody, Dester_1490 antibody, ARCVE_RS05445 antibody, Mahau_1873 antibody, MZHIL_RS01440 antibody, mtap antibody, mtap.L antibody

Background:

Description: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.

Gene: MTAP

Molecular Weight: 31kDa

Gene ID: 4507

UniProt: Q13126

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process