Mitochondrially Encoded ATP Synthase 8 (MT-ATP8) (Internal Region) antibody

Catalog No. ABIN6263408

Product Details

Target: Mitochondrially Encoded ATP Synthase 8 (MT-ATP8)

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: MT-ATP8 Antibody detects endogenous levels of total MT-ATP8.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MT-ATP8, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details

Target: Mitochondrially Encoded ATP Synthase 8 (MT-ATP8)

Alternative Name: MT-ATP8 (MT-ATP8 Products)

Synonyms: mtatp8 antibody, ATPase 8 antibody, ATPase8 antibody, MTATP8 antibody, ATP synthase F0 subunit 8 antibody, ATP synthase 8 antibody, ATPase subunit 8 antibody, ATP8 antibody

Background:

Description: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane (By similarity).

Gene: MT-ATP8

Molecular Weight: 8 kDa

Gene ID: 4509

UniProt: P03928

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process