MRC2 antibody (N-Term)
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- Target See all MRC2 Antibodies
- MRC2 (Mannose Receptor, C Type 2 (MRC2))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MRC2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MRC2 Antibody detects endogenous levels of total MRC2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MRC2, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MRC2 (Mannose Receptor, C Type 2 (MRC2))
- Alternative Name
- MRC2 (MRC2 Products)
- Synonyms
- MRC2 antibody, cd280 antibody, uparap antibody, clec13e antibody, endo180 antibody, Endo180 antibody, CD280 antibody, CLEC13E antibody, ENDO180 antibody, UPARAP antibody, mKIAA0709 antibody, uPARAP antibody, mannose receptor C type 2 antibody, mannose receptor, C type 2 antibody, MRC2 antibody, mrc2 antibody, Mrc2 antibody
- Background
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Description: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
Gene: MRC2
- Molecular Weight
- 167kDa
- Gene ID
- 9902
- UniProt
- Q9UBG0
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