MGMT antibody (N-Term)
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- Target See all MGMT Antibodies
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MGMT antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- MGMT Antibody detects endogenous levels of total MGMT.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MGMT, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product MGMT Primary Antibody
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anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 32-210) antibody
MGMT Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 1A11F8 unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 101-207) antibodyMGMT Reactivity: Rat WB, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182), (C-Term) antibodyMGMT Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19082 unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 156-182) antibodyMGMT Reactivity: Human WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibodyMGMT Reactivity: Rat, Mouse IHC Host: Rabbit Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (AA 1-207) antibodyMGMT Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) (N-Term) antibodyMGMT Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
- Alternative Name
- MGMT (MGMT Products)
- Synonyms
- AGT antibody, AI267024 antibody, Agat antibody, O-6-methylguanine-DNA methyltransferase antibody, MGMT antibody, Mgmt antibody
- Background
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Description: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Gene: MGMT
- Molecular Weight
- 22 kDa
- Gene ID
- 4255
- UniProt
- P16455
- Pathways
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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