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MESDC2 antibody (Internal Region)

MESDC2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6263227
  • Target See all MESDC2 Antibodies
    MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
    Binding Specificity
    • 8
    • 7
    • 7
    • 3
    • 1
    Internal Region
    Reactivity
    • 27
    • 3
    • 1
    • 1
    Human, Mouse
    Host
    • 25
    • 3
    • 1
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MESDC2 antibody is un-conjugated
    Application
    • 22
    • 14
    • 14
    • 13
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    MESDC2 Antibody detects endogenous levels of total MESDC2.
    Predicted Reactivity
    Zebrafish,Bovine,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human MESDC2, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product MESDC2 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
    Alternative Name
    MESDC2 (MESDC2 Products)
    Synonyms
    MGC115616 antibody, MESDC2 antibody, BOCA antibody, MESD antibody, 2210015O11Rik antibody, AW537813 antibody, mKIAA0081 antibody, mesd antibody, msd antibody, zgc:158636 antibody, mesoderm development LRP chaperone antibody, mesoderm development LRP chaperone L homeolog antibody, mesoderm development candidate 2 antibody, MESD antibody, mesd.L antibody, CpipJ_CPIJ010816 antibody, Tsp_04045 antibody, mesd antibody, Mesd antibody, MESDC2 antibody
    Background

    Description: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).

    Gene: MESDC2

    Molecular Weight
    26 kDa
    Gene ID
    23184
    UniProt
    Q14696
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