CCL2 antibody (Internal Region)
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- Target See all CCL2 Antibodies
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCL2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- MCP1 Antibody detects endogenous levels of total MCP1.
- Predicted Reactivity
- Horse
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MCP1, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CCL2 Primary Antibody
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- Application Notes
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction." in: Transplant immunology, Vol. 48, pp. 18-25, (2018) (PubMed).
: "An Extracellular Matrix-Mimicking Hydrogel for Full Thickness Wound Healing in Diabetic Mice." in: Macromolecular bioscience, Vol. 18, Issue 7, pp. e1800047, (2018) (PubMed).
: "[Comparative estimation of antilithogenic activity of porcine kidney derived biomedical substance and sodium citrate in experimental urolithiasis]." in: Urologiia (Moscow, Russia : 1999), Issue 2, pp. 24-27, (2017) (PubMed).
: "Urinary MCP-1、HMGB1 increased in calcium nephrolithiasis patients and the influence of hypercalciuria on the production of the two cytokines." in: Urolithiasis, Vol. 45, Issue 2, pp. 159-175, (2016) (PubMed).
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Expression and significance of Sirt1 in renal allografts at the early stage of chronic renal allograft dysfunction." in: Transplant immunology, Vol. 48, pp. 18-25, (2018) (PubMed).
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- Target
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
- Alternative Name
- CCL2 (CCL2 Products)
- Synonyms
- GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody
- Background
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Description: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
Gene: CCL2
- Molecular Weight
- 14 kDa
- Gene ID
- 6347
- UniProt
- P13500
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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