MCM10 antibody (C-Term)
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- Target See all MCM10 Antibodies
- MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MCM10 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- MCM10 Antibody detects endogenous levels of total MCM10.
- Predicted Reactivity
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MCM10, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
- Alternative Name
- MCM10 (MCM10 Products)
- Background
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Description: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability, acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).
Gene: MCM10
- Molecular Weight
- 97-105 kDa
- Gene ID
- 55388
- UniProt
- Q7L590
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication
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