ST14 antibody (Internal Region)

Catalog No. ABIN6263143

Product Details anti-ST14 Antibody

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: Matriptase Antibody detects endogenous levels of total Matriptase.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Matriptase, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ST14

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Alternative Name: ST14 (ST14 Products)

Synonyms: HAI antibody, MT-SP1 antibody, MTSP1 antibody, PRSS14 antibody, SNC19 antibody, TADG15 antibody, TMPRSS14 antibody, XMT-SP1 antibody, hai antibody, mt-sp1 antibody, mtsp1 antibody, prss14 antibody, snc19 antibody, st14 antibody, st14a antibody, tadg15 antibody, tmprss1 antibody, Epithin antibody, Prss14 antibody, Tmprss14 antibody, mCAP3 antibody, matriptase antibody, suppression of tumorigenicity 14 antibody, suppression of tumorigenicity 14 L homeolog antibody, suppression of tumorigenicity 14 (colon carcinoma) antibody, ST14 antibody, st14.L antibody, St14 antibody

Background:

Description: Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.

Gene: ST14

Molecular Weight: 95kDa

Gene ID: 6768

UniProt: Q9Y5Y6