MAT2B antibody (Internal Region)

Catalog No. ABIN6263142

Product Details anti-MAT2B Antibody

Target: MAT2B (Methionine Adenosyltransferase II, beta (MAT2B))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAT2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: MAT2B Antibody detects endogenous levels of total MAT2B.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAT2B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MAT2B

Target: MAT2B (Methionine Adenosyltransferase II, beta (MAT2B))

Alternative Name: MAT2B (MAT2B Products)

Synonyms: MAT-II antibody, MATIIbeta antibody, Nbla02999 antibody, SDR23E1 antibody, TGR antibody, 1110064C04Rik antibody, 2410018D16Rik antibody, AI182287 antibody, AU022853 antibody, fc55d01 antibody, wu:fb48h02 antibody, wu:fc55d01 antibody, zgc:110308 antibody, MAT2beta antibody, methionine adenosyltransferase 2B antibody, methionine adenosyltransferase II, beta antibody, methionine adenosyltransferase II, beta L homeolog antibody, MAT2B antibody, Mat2b antibody, mat2b antibody, mat2b.L antibody

Background:

Description: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine (PubMed:10644686, PubMed:23189196, PubMed:25075345). Can bind NADP (in vitro) (PubMed:23189196, PubMed:23425511).

Gene: MAT2B

Molecular Weight: 38 kDa

Gene ID: 27430

UniProt: Q9NZL9

Pathways: Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process, SARS-CoV-2 Protein Interactome