MAP1B antibody (Internal Region)

Catalog No. ABIN6263094

Product Details anti-MAP1B Antibody

Target: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: MAP1B Antibody detects endogenous levels of total MAP1B.

Predicted Reactivity: Pig,Zebrafish,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAP1B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MAP1B

Target: MAP1B (Microtubule-Associated Protein 1B (MAP1B))

Alternative Name: MAP1B (MAP1B Products)

Synonyms: FUTSCH antibody, MAP5 antibody, Mtap1b antibody, A230055D22 antibody, AI843217 antibody, LC1 antibody, Mtap-5 antibody, Mtap5 antibody, microtubule associated protein 1B antibody, microtubule-associated protein 1B antibody, MAP1B antibody, Map1b antibody

Background:

Description: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

Gene: MAP1B

Molecular Weight: 320 kDa

Gene ID: 4131

UniProt: P46821

Pathways: Microtubule Dynamics, Regulation of Cell Size