CHRM4 antibody (Internal Region)

Catalog No. ABIN6263046

Product Details anti-CHRM4 Antibody

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: CHRM4 Antibody detects endogenous levels of total CHRM4.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CHRM4, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CHRM4

Target: CHRM4 (Cholinergic Receptor, Muscarinic 4 (CHRM4))

Alternative Name: CHRM4 (CHRM4 Products)

Synonyms: M3R antibody, M4 antibody, HM4 antibody, M4R antibody, Chrm-4 antibody, cholinergic receptor muscarinic 4 antibody, cholinergic receptor, muscarinic 4 antibody, CHRM4 antibody, chrm4 antibody, Chrm4 antibody

Background:

Description: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.

Gene: CHRM4

Molecular Weight: 53kDa

Gene ID: 1132

UniProt: P08173

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Synaptic Membrane