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K-RAS antibody (C-Term)

KRAS Reactivity: Human, Rat, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262871
  • Target See all K-RAS (KRAS) Antibodies
    K-RAS (KRAS) (GTPase Kras (KRAS))
    Binding Specificity
    • 16
    • 11
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 59
    • 38
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 62
    • 10
    Rabbit
    Clonality
    • 62
    • 10
    Polyclonal
    Conjugate
    • 29
    • 7
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This K-RAS antibody is un-conjugated
    Application
    • 62
    • 28
    • 23
    • 13
    • 13
    • 13
    • 9
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    KRAS Antibody detects endogenous levels of total KRAS.
    Predicted Reactivity
    Rabbit,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human KRAS, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product KRAS Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    K-RAS (KRAS) (GTPase Kras (KRAS))
    Alternative Name
    KRAS (KRAS Products)
    Target Type
    Viral Protein
    Background

    Description: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).

    Gene: KRAS

    Molecular Weight
    21kDa
    Gene ID
    3845
    UniProt
    P01116
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