KIF2C antibody (C-Term)

Catalog No. ABIN6262808

Product Details anti-KIF2C Antibody

Target: KIF2C (Kinesin Family Member 2C (KIF2C))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificity: KIF2C Antibody detects endogenous levels of total KIF2C.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KIF2C, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for KIF2C

Target: KIF2C (Kinesin Family Member 2C (KIF2C))

Alternative Name: KIF2C (KIF2C Products)

Synonyms: kif2c antibody, MGC89391 antibody, KIF2C antibody, si:ch211-61f14.1 antibody, KNSL6 antibody, MCAK antibody, 4930402F02Rik antibody, ESTM5 antibody, Knsl6 antibody, X83316 antibody, KRP2 antibody, kcm1 antibody, mcak antibody, kinesin family member 2C antibody, kinesin family member 2C S homeolog antibody, KIF2C antibody, kif2c antibody, Kif2c antibody, kif2c.S antibody

Background:

Description: In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309). Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894). Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108).

Gene: KIF2C

Molecular Weight: 81kDa

Gene ID: 11004

UniProt: Q99661

Pathways: Microtubule Dynamics