KCTD12 antibody (Internal Region)

Catalog No. ABIN6262762

Product Details anti-KCTD12 Antibody

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: KCTD12 Antibody detects endogenous levels of total KCTD12.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCTD12, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for KCTD12

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Alternative Name: KCTD12 (KCTD12 Products)

Background:

Description: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

Gene: KCTD12

Molecular Weight: 36 kDa

Gene ID: 115207

UniProt: Q96CX2

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling