KCTD12 antibody (Internal Region)

Catalog No. ABIN6262762

Product Details anti-KCTD12 Antibody

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: KCTD12 Antibody detects endogenous levels of total KCTD12.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCTD12, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for KCTD12

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Alternative Name: KCTD12 (KCTD12 Products)

Synonyms: AU046135 antibody, AW538430 antibody, Pfet1 antibody, Pfetin antibody, C13orf2 antibody, PFET1 antibody, PFETIN antibody, potassium channel tetramerisation domain containing 12 antibody, potassium channel tetramerization domain containing 12 antibody, Kctd12 antibody, KCTD12 antibody

Background:

Description: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).

Gene: KCTD12

Molecular Weight: 36 kDa

Gene ID: 115207

UniProt: Q96CX2

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling