Integrin beta 4 antibody (C-Term)
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- Target See all Integrin beta 4 (ITGB4) Antibodies
- Integrin beta 4 (ITGB4)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Integrin beta 4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Integrin beta 4 Antibody detects endogenous levels of total Integrin beta 4.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Integrin beta 4, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ITGB4 Primary Antibody
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anti-Integrin beta 4 (ITGB4) (AA 1619-1822) antibody
ITGB4 Reactivity: Human WB, IHC, FACS, ELISA Host: Mouse Monoclonal 10B10D5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 29-206) antibodyITGB4 Reactivity: Human WB, IHC, FACS, ELISA Host: Mouse Monoclonal 5G3G5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1401-1533) antibodyITGB4 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-310) antibodyITGB4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (Tyr1510) antibodyITGB4 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-137) antibodyITGB4 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1098-1356) antibodyITGB4 Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-266) antibodyITGB4 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (Tyr1510) antibodyITGB4 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (pTyr1494) antibodyITGB4 Reactivity: Rat ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- Integrin beta 4 (ITGB4)
- Alternative Name
- ITGB4 (ITGB4 Products)
- Synonyms
- AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
- Background
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Description: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).
Gene: ITGB4
- Molecular Weight
- 202 kDa
- Gene ID
- 3691
- UniProt
- P16144
- Pathways
- Integrin Complex
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