INSRR antibody (N-Term)

Catalog No. ABIN6262604

Product Details anti-INSRR Antibody

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSRR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: INSRR Antibody detects endogenous levels of total INSRR.

Predicted Reactivity: Pig,Bovine,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human INSRR, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for INSRR

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Alternative Name: INSRR (INSRR Products)

Synonyms: IRR antibody, Irr antibody, Sirr antibody, MGC68585 antibody, INSRR antibody, insulin receptor related receptor antibody, insulin receptor-related receptor antibody, insulin receptor related receptor L homeolog antibody, INSRR antibody, Insrr antibody, insrr.L antibody, insrr antibody

Background:

Description: Receptor with tyrosine-protein kinase activity. Functions as a  pH sensing receptor which is activated by increased extracellular  pH . Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Gene: INSRR

Molecular Weight: 155 kDa

Gene ID: 3645

UniProt: P14616

Pathways: RTK Signaling