ING2 antibody (C-Term)
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- Target See all ING2 Antibodies
- ING2 (Inhibitor of Growth Family, Member 2 (ING2))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ING2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- ING2 Antibody detects endogenous levels of total ING2.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ING2, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ING2 Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ING2 (Inhibitor of Growth Family, Member 2 (ING2))
- Alternative Name
- ING2 (ING2 Products)
- Synonyms
- ING1L antibody, p33ING2 antibody, 2810011M06Rik antibody, Ing1l antibody, Ing2b antibody, P33ING2 antibody, ING2 antibody, INGX antibody, wu:fe11c08 antibody, zgc:92346 antibody, ING1Lp antibody, ing2 antibody, xing2 antibody, inhibitor of growth family member 2 antibody, inhibitor of growth family, member 2 antibody, inhibitor of growth family member 2 S homeolog antibody, inhibitor of growth family member 2 L homeolog antibody, ING2 antibody, Ing2 antibody, ing2.S antibody, ing2 antibody, ing2.L antibody
- Background
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Description: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
Gene: ING2
- Molecular Weight
- 33 kDa
- Gene ID
- 3622
- UniProt
- Q9H160
- Pathways
- Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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