IL31RA antibody (Internal Region)
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- Target See all IL31RA Antibodies
- IL31RA (Interleukin 31 Receptor A (IL31RA))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IL31RA antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- IL31R Antibody detects endogenous levels of total IL31R.
- Predicted Reactivity
- Pig,Bovine,Sheep,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human IL31R, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product IL31RA Primary Antibody
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- Application Notes
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- IL31RA (Interleukin 31 Receptor A (IL31RA))
- Alternative Name
- IL31RA (IL31RA Products)
- Synonyms
- IL31RA antibody, CRL antibody, CRL3 antibody, GLM-R antibody, GLMR antibody, GPL antibody, IL-31RA antibody, PLCA2 antibody, PRO21384 antibody, hGLM-R antibody, Glmr antibody, NR10 antibody, interleukin 31 receptor A antibody, IL31RA antibody, Il31ra antibody
- Background
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Description: Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5 (PubMed:11877449, PubMed:14504285, PubMed:15627637, PubMed:15194700). May function in skin immunity (PubMed:15184896). Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1 (By similarity). Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro (By similarity).
Gene: IL31RA
- Molecular Weight
- 83 kDa
- Gene ID
- 133396
- UniProt
- Q8NI17
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