IFT140 antibody (Internal Region)

Catalog No. ABIN6262477

Product Details anti-IFT140 Antibody

Target: IFT140 (Intraflagellar Transport 140 Homolog (IFT140))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT140 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: IFT140 Antibody detects endogenous levels of total IFT140.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IFT140, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IFT140

Target: IFT140 (Intraflagellar Transport 140 Homolog (IFT140))

Alternative Name: IFT140 (IFT140 Products)

Synonyms: zC153C20.3 antibody, si:ch211-153c20.3 antibody, gs114 antibody, wdtc2 antibody, c305c8.4 antibody, c380f5.1 antibody, AI661311 antibody, Tce5 antibody, Wdtc2 antibody, mKIAA0590 antibody, MZSDS antibody, WDTC2 antibody, c305C8.4 antibody, c380F5.1 antibody, intraflagellar transport 140 homolog (Chlamydomonas) antibody, intraflagellar transport 140 antibody, intraflagellar transport protein 140 homolog antibody, ift140 antibody, IFT140 antibody, LOC100636864 antibody, LOC100645502 antibody, Ift140 antibody

Background:

Description: Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance (PubMed:22503633). May play a role in ciliary assembly. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (By similarity).

Gene: IFT140

Molecular Weight: 140 kDa

Gene ID: 9742

UniProt: Q96RY7

Pathways: Hedgehog Signaling