HSPH1 antibody (C-Term)

Catalog No. ABIN6262389

Product Details anti-HSPH1 Antibody

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: HSP105 Antibody detects endogenous levels of total HSP105.

Predicted Reactivity: Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HSP105, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Alternative Name: HSPH1 (HSPH1 Products)

Synonyms: hsp105 antibody, hsp105a antibody, hsp105b antibody, hsp110 antibody, hsph1b antibody, Hsp105 antibody, HSP105 antibody, HSP105A antibody, HSP105B antibody, NY-CO-25 antibody, 105kDa antibody, AI790491 antibody, Hsp110 antibody, hsp-E7I antibody, hsph1 antibody, hsph1a antibody, heat shock protein family H (Hsp110) member 1 antibody, heat shock protein family H (Hsp110) member 1 S homeolog antibody, heat shock protein 105 kDa antibody, heat shock 105kDa/110kDa protein 1 antibody, heat shock protein family H (Hsp110) member 1 L homeolog antibody, hsph1 antibody, hsph1.S antibody, HSPH1 antibody, LOC100546590 antibody, Hsph1 antibody, hsph1.L antibody

Background:

Description: Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).

Gene: HSPH1

Molecular Weight: 100kDa

Gene ID: 10808

UniProt: Q92598