HSD17B12 antibody (Internal Region)
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- Target See all HSD17B12 Antibodies
- HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSD17B12 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- HSD17B12 Antibody detects endogenous levels of total HSD17B12.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HSD17B12, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HSD17B12 Primary Antibody
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- Application Notes
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))
- Alternative Name
- HSD17B12 (HSD17B12 Products)
- Synonyms
- KAR antibody, SDR12C1 antibody, 2610510O05Rik antibody, AI172963 antibody, KIK-I antibody, Kik1 antibody, HSD17B12 antibody, kar antibody, sdr12c1 antibody, 17-beta-HSD 12-A antibody, fi06g11 antibody, wu:fi06g11 antibody, zf3.1 antibody, zfHSD17B12A antibody, zgc:55589 antibody, zgc:77599 antibody, hydroxysteroid 17-beta dehydrogenase 12 antibody, hydroxysteroid (17-beta) dehydrogenase 12 antibody, hydroxysteroid (17-beta) dehydrogenase 12 L homeolog antibody, hydroxysteroid (17-beta) dehydrogenase 12a antibody, HSD17B12 antibody, Hsd17b12 antibody, hsd17b12.L antibody, hsd17b12a antibody
- Background
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Description: Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.
Gene: HSD17B12
- Molecular Weight
- 34 kDa
- Gene ID
- 51144
- UniProt
- Q53GQ0
- Pathways
- Steroid Hormone Biosynthesis
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