HMGB3 antibody (Internal Region)
-
- Target See all HMGB3 Antibodies
- HMGB3 (High Mobility Group Box 3 (HMGB3))
-
Binding Specificity
- Internal Region
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HMGB3 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- HMGB3 Antibody detects endogenous levels of total HMGB3.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HMGB3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HMGB3 Primary Antibody
-
anti-High Mobility Group Box 3 (HMGB3) (AA 1-103) antibody
HMGB3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 62-95), (N-Term) antibodyHMGB3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 1-200) antibodyHMGB3 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (C-Term) antibodyHMGB3 Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Rabbit, Pig, Guinea Pig, Zebrafish (Danio rerio), Chicken, Hamster, Monkey, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 150-200) antibodyHMGB3 Reactivity: Human, Mouse, Cow, Horse, Dog, Chicken WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 14-176) antibodyHMGB3 Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) antibodyHMGB3 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (Internal Region) antibodyVerified HMGB3 Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-High Mobility Group Box 3 (HMGB3) (AA 1-50) antibodyHMGB3 Reactivity: Human, Mouse, Rat, Cow, Horse, Opossum WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- HMGB3 (High Mobility Group Box 3 (HMGB3))
- Alternative Name
- HMGB3 (HMGB3 Products)
- Background
-
Description: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling (By similarity).
Gene: HMGB3
- Molecular Weight
- 23 kDa
- Gene ID
- 3149
- UniProt
- O15347
-
