HJURP antibody (C-Term)

Catalog No. ABIN6262279

Product Details anti-HJURP Antibody

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HJURP antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: HJURP Antibody detects endogenous levels of total HJURP.

Predicted Reactivity: Pig,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HJURP, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for HJURP

Target: HJURP (Holliday Junction Recognition Protein (HJURP))

Alternative Name: HJURP (HJURP Products)

Synonyms: Gm975 antibody, Mfleg1 antibody, MGC66590 antibody, C330011F01Rik antibody, FAKTS antibody, URLC9 antibody, hFLEG1 antibody, Holliday junction recognition protein antibody, Hjurp antibody, HJURP antibody

Background:

Description: Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.

Gene: HJURP

Molecular Weight: 84 kDa

Gene ID: 55355

UniProt: Q8NCD3