HDAC8 antibody (N-Term)
-
- Target See all HDAC8 Antibodies
- HDAC8 (Histone Deacetylase 8 (HDAC8))
-
Binding Specificity
- N-Term
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This HDAC8 antibody is un-conjugated
-
Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- HDAC8 Antibody detects endogenous levels of total HDAC8.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human HDAC8, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HDAC8 Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Alternative Name
- HDAC8 (HDAC8 Products)
- Synonyms
- HD8 antibody, CDLS5 antibody, HDACL1 antibody, MRXS6 antibody, RPD3 antibody, WTS antibody, 2610007D20Rik antibody, RGD1562895 antibody, wu:fd19a02 antibody, zgc:66196 antibody, ATHDA8 antibody, HDA8 antibody, HISTONE DEACETYLASE 8 antibody, T27G7.14 antibody, T27G7_14 antibody, histone deacetylase 8 antibody, histone deacetylase 8 antibody, histone deacetylase 8 L homeolog antibody, CC1G_05302 antibody, hdac8 antibody, HDAC8 antibody, Hdac8 antibody, hdac8.L antibody, HDA08 antibody
- Background
-
Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
Gene: HDAC8
- Molecular Weight
- 42kDa
- Gene ID
- 55869
- UniProt
- Q9BY41
- Pathways
- Cellular Glucan Metabolic Process
-