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GDF11 antibody (Internal Region)

GDF11 Reactivity: Human, Mouse WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261926
  • Target See all GDF11 Antibodies
    GDF11 (Growth Differentiation Factor 11 (GDF11))
    Binding Specificity
    • 14
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Internal Region
    Reactivity
    • 39
    • 13
    • 12
    • 6
    Human, Mouse
    Host
    • 39
    • 9
    Rabbit
    Clonality
    • 40
    • 8
    Polyclonal
    Conjugate
    • 23
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDF11 antibody is un-conjugated
    Application
    • 30
    • 25
    • 22
    • 8
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    GDF11 Antibody detects endogenous levels of total GDF11.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GDF11, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GDF11 Primary Antibody
  • Application Notes
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    GDF11 (Growth Differentiation Factor 11 (GDF11))
    Alternative Name
    GDF11 (GDF11 Products)
    Synonyms
    BMP-11 antibody, BMP11 antibody, Bmp11 antibody, GDF11 antibody, growth differentiation factor 11 antibody, GDF11 antibody, Gdf11 antibody, gdf11 antibody
    Background

    Description: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).

    Gene: GDF11

    Molecular Weight
    45 kDa
    Gene ID
    10220
    UniProt
    O95390
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