GDF11 antibody (Internal Region)
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- Target See all GDF11 Antibodies
- GDF11 (Growth Differentiation Factor 11 (GDF11))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GDF11 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- Specificity
- GDF11 Antibody detects endogenous levels of total GDF11.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GDF11, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GDF11 Primary Antibody
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- Application Notes
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Alternative Name
- GDF11 (GDF11 Products)
- Synonyms
- BMP-11 antibody, BMP11 antibody, Bmp11 antibody, GDF11 antibody, growth differentiation factor 11 antibody, GDF11 antibody, Gdf11 antibody, gdf11 antibody
- Background
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Description: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).
Gene: GDF11
- Molecular Weight
- 45 kDa
- Gene ID
- 10220
- UniProt
- O95390
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