GAB2 antibody (C-Term)
-
- Target See all GAB2 Antibodies
- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This GAB2 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Gab2 Antibody detects endogenous levels of total Gab2.
- Predicted Reactivity
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human Gab2, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product GAB2 Primary Antibody
-
-
- Application Notes
- WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
-
- Target
- GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
- Alternative Name
- GAB2 (GAB2 Products)
- Synonyms
- GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
- Background
-
Description: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Gene: GAB2
- Molecular Weight
- 97kDa
- Gene ID
- 9846
- UniProt
- Q9UQC2
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
-