Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GAB2 antibody (C-Term)

GAB2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261848
  • Target See all GAB2 Antibodies
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Binding Specificity
    • 24
    • 21
    • 16
    • 11
    • 10
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 123
    • 90
    • 84
    • 3
    • 3
    • 3
    • 3
    Human, Mouse, Rat
    Host
    • 121
    • 2
    • 1
    Rabbit
    Clonality
    • 123
    • 1
    Polyclonal
    Conjugate
    • 40
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This GAB2 antibody is un-conjugated
    Application
    • 85
    • 40
    • 39
    • 39
    • 20
    • 15
    • 13
    • 9
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificity
    Gab2 Antibody detects endogenous levels of total Gab2.
    Predicted Reactivity
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Gab2, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product GAB2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    GAB2 (GRB2-Associated Binding Protein 2 (GAB2))
    Alternative Name
    GAB2 (GAB2 Products)
    Synonyms
    GAB2 antibody, AI463667 antibody, D130058I17Rik antibody, p97 antibody, GRB2 associated binding protein 2 antibody, GRB2-associated binding protein 2 antibody, growth factor receptor bound protein 2-associated protein 2 antibody, GAB2 antibody, gab2 antibody, Gab2 antibody
    Background

    Description: Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

    Gene: GAB2

    Molecular Weight
    97kDa
    Gene ID
    9846
    UniProt
    Q9UQC2
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, Warburg Effect
You are here:
Support