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FYB antibody

FYB Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IF, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261835
  • Target See all FYB Antibodies
    FYB (FYN-Binding Protein (FYB))
    Reactivity
    • 49
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 42
    • 6
    • 1
    Rabbit
    Clonality
    • 43
    • 6
    Polyclonal
    Conjugate
    • 25
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FYB antibody is un-conjugated
    Application
    • 33
    • 24
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
    Specificity
    FYB Antibody detects endogenous levels of total FYB
    Cross-Reactivity
    Human, Mouse (Murine), Rat (Rattus)
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human FYB
    Isotype
    IgG
  • Application Notes
    WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C.Stable for 12 months from date of receipt
    Expiry Date
    12 months
  • Target
    FYB (FYN-Binding Protein (FYB))
    Alternative Name
    FYB (FYB Products)
    Synonyms
    fyb antibody, ADAP antibody, PRO0823 antibody, SLAP-130 antibody, B630013F22Rik antibody, FYB-120/130 antibody, Slap130 antibody, p120/130 antibody, p120/p130 antibody, RGD1563421 antibody, FYN-binding protein antibody, FYN binding protein 1 antibody, FYN binding protein antibody, fyb antibody, FYB1 antibody, Fyb antibody, Fyb1 antibody
    Background

    Description: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.

    Gene: FYB1

    Molecular Weight
    110 kDa
    Gene ID
    2533
    UniProt
    O15117
    Pathways
    TCR Signaling, Protein targeting to Nucleus
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