FYB antibody
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- Target See all FYB Antibodies
- FYB (FYN-Binding Protein (FYB))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FYB antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Specificity
- FYB Antibody detects endogenous levels of total FYB
- Cross-Reactivity
- Human, Mouse (Murine), Rat (Rattus)
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human FYB
- Isotype
- IgG
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- Application Notes
- WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- FYB (FYN-Binding Protein (FYB))
- Alternative Name
- FYB (FYB Products)
- Synonyms
- fyb antibody, ADAP antibody, PRO0823 antibody, SLAP-130 antibody, B630013F22Rik antibody, FYB-120/130 antibody, Slap130 antibody, p120/130 antibody, p120/p130 antibody, RGD1563421 antibody, FYN-binding protein antibody, FYN binding protein 1 antibody, FYN binding protein antibody, fyb antibody, FYB1 antibody, Fyb antibody, Fyb1 antibody
- Background
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Description: Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
Gene: FYB1
- Molecular Weight
- 110 kDa
- Gene ID
- 2533
- UniProt
- O15117
- Pathways
- TCR Signaling, Protein targeting to Nucleus
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