FKRP antibody (N-Term)

Catalog No. ABIN6261761

Product Details anti-FKRP Antibody

Target: FKRP (Fukutin Related Protein (FKRP))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKRP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Specificity: FKRP Antibody detects endogenous levels of total FKRP.

Predicted Reactivity: Pig,Bovine,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FKRP, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FKRP

Target: FKRP (Fukutin Related Protein (FKRP))

Alternative Name: FKRP (FKRP Products)

Synonyms: zgc:162829 antibody, LGMD2I antibody, MDC1C antibody, MDDGA5 antibody, MDDGB5 antibody, MDDGC5 antibody, A830029B19Rik antibody, AI842067 antibody, AI847300 antibody, LGMD1I antibody, fukutin related protein antibody, FKRP antibody, fkrp antibody, Fkrp antibody

Background:

Description: Transferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.

Gene: FKRP

Molecular Weight: 50kDa

Gene ID: 79147

UniProt: Q9H9S5

Pathways: Regulation of Carbohydrate Metabolic Process