FKBP1A antibody (N-Term)
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- Target See all FKBP1A Antibodies
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FKBP1A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- FKBP1A Antibody detects endogenous levels of total FKBP1A.
- Predicted Reactivity
- Pig,Bovine,Rabbit,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human FKBP1A, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product FKBP1A Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
- Alternative Name
- FKBP1A (FKBP1A Products)
- Background
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Description: Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Gene: FKBP1A
- Molecular Weight
- 12kDa
- Gene ID
- 2280
- UniProt
- P62942
- Pathways
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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