FARP2 antibody (Internal Region)

Catalog No. ABIN6261751

Product Details anti-FARP2 Antibody

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FARP2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: FIR Antibody detects endogenous levels of total FIR.

Predicted Reactivity: Pig,Horse,Sheep,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FIR, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for FARP2

Target: FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))

Alternative Name: FARP2 (FARP2 Products)

Synonyms: FARP2 antibody, wu:fc23d05 antibody, wu:fp25d09 antibody, MGC131000 antibody, FIR antibody, FRG antibody, PLEKHC3 antibody, AI465173 antibody, BC009153 antibody, D030026M03Rik antibody, Fir antibody, mKIAA0793 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 antibody, FERM, RhoGEF and pleckstrin domain protein 2 antibody, FERM, ARH/RhoGEF and pleckstrin domain protein 2 L homeolog antibody, FARP2 antibody, farp2 antibody, farp2.L antibody, Farp2 antibody

Background:

Description: Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity).

Gene: FARP2

Molecular Weight: 119kDa

Gene ID: 9855

UniProt: O94887