ETAA1 antibody (Internal Region)

Catalog No. ABIN6261612

Product Details anti-ETAA1 Antibody

Target: ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ETAA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: ETAA1 Antibody detects endogenous levels of total ETAA1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ETAA1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ETAA1

Target: ETAA1 (Ewing Tumor-Associated Antigen 1 (ETAA1))

Alternative Name: ETAA1 (ETAA1 Products)

Synonyms: ETAA16 antibody, ETAA1 antibody, 5730466H23Rik antibody, AA672646 antibody, etaa1 antibody, MGC145507 antibody, MGC81344 antibody, RGD1560957 antibody, zgc:171518 antibody, ETAA1, ATR kinase activator antibody, Ewing tumor-associated antigen 1 antibody, Ewing tumor associated antigen 1 antibody, ETAA1, ATR kinase activator L homeolog antibody, ETAA1 antibody, Etaa1 antibody, etaa1 antibody, etaa1.L antibody

Background:

Description: Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).

Gene: ETAA1

Molecular Weight: 103 kDa

Gene ID: 54465

UniProt: Q9NY74