EOMES antibody (C-Term)

Catalog No. ABIN6261546

Product Details anti-EOMES Antibody

Target: EOMES (Eomesodermin (EOMES))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: EOMES Antibody detects endogenous levels of total EOMES.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EOMES, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: EOMES (EOMES Products)

Synonyms: TBR2 antibody, eom antibody, eomes antibody, EOMES antibody, xeomes antibody, tbr2 antibody, C77258 antibody, TBR-2 antibody, Tbr2 antibody, eomesodermin antibody, eomesodermin homolog a antibody, eomesodermin L homeolog antibody, EOMES antibody, eomesa antibody, Eomes antibody, eomes.L antibody, eomes antibody

Background:

Description: Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.

Gene: EOMES

Molecular Weight: 72 kDa

Gene ID: 8320

UniProt: O95936

Pathways: Stem Cell Maintenance