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EIF4E antibody (C-Term)

EIF4E Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6261494
  • Target See all EIF4E Antibodies
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Binding Specificity
    • 37
    • 15
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 114
    • 54
    • 42
    • 19
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Rat, Mouse
    Host
    • 98
    • 15
    • 2
    Rabbit
    Clonality
    • 91
    • 24
    Polyclonal
    Conjugate
    • 55
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF4E antibody is un-conjugated
    Application
    • 94
    • 49
    • 39
    • 27
    • 27
    • 26
    • 17
    • 14
    • 14
    • 12
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    EIF4E Antibody detects endogenous levels of total eIF4E.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human eIF4E, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product EIF4E Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Alternative Name
    EIF4E (EIF4E Products)
    Background

    Description: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.

    Gene: EIF4E

    Molecular Weight
    25kDa
    Gene ID
    1977
    UniProt
    P06730
    Pathways
    BCR Signaling
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