EDEM2 antibody
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- Target See all EDEM2 Antibodies
- EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EDEM2 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Specificity
- EDEM2 Antibody detects endogenous levels of total EDEM2
- Cross-Reactivity
- Human
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human EDEM2
- Isotype
- IgG
- Top Product
- Discover our top product EDEM2 Primary Antibody
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- Application Notes
- WB 1:1000-3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C.Stable for 12 months from date of receipt
- Expiry Date
- 12 months
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- Target
- EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))
- Alternative Name
- EDEM2 (EDEM2 Products)
- Synonyms
- C20orf31 antibody, C20orf49 antibody, bA4204.1 antibody, 9530090G24Rik antibody, AI327354 antibody, RGD1303074 antibody, MGC88910 antibody, DKFZp459A0314 antibody, ER degradation enhancing alpha-mannosidase like protein 2 antibody, ER degradation enhancer, mannosidase alpha-like 2 antibody, EDEM2 antibody, Edem2 antibody, edem2 antibody
- Background
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Description: Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Gene: EDEM2
- Molecular Weight
- 65 kDa
- Gene ID
- 55741
- UniProt
- Q9BV94
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